Class 3 Drugs List
Naphyrone (and the related drugs NRG-1 and NRG-3) is a Class B, Schedule 1 drug. It is illegal to possess, supply or produce. Possession of Class B drugs carry a maximum sentence of 5 years’ imprisonment and a fine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Drugs affecting the cardiac action potential. The sharp rise in voltage ('0') corresponds to the influx of sodium ions, whereas the two decays ('1' and '3', respectively) correspond to the sodium-channel inactivation and the repolarizing efflux of potassium ions. The characteristic plateau ('2') results from the opening of voltage-sensitive channels. Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of that are used to suppress abnormal rhythms of the (), such as,,,.
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Guru randhawa song made in india song video. Many attempts have been made to classify antiarrhythmic agents. The problem arises from the fact that many of the antiarrhythmic agents have multiple modes of action, making any classification imprecise. Contents • • • • • • • • • • • Vaughan Williams classification [ ] The Vaughan Williams classification was introduced in 1970.
Miles was the tutor for Pharmacology at, Oxford; one of his students,, contributed to the development of the classification system, and had a subsequent eminent career in the United States; the system is therefore sometimes known as the Singh-Vaughan Williams classification. The five main classes in the Vaughan Williams classification of antiarrhythmic agents are: • Class I agents interfere with the (Na +) channel. • Class II agents are anti- agents. Most agents in this class are. • Class III agents affect (K +) efflux. • Class IV agents affect channels and the. • Class V agents work by other or unknown mechanisms.
With regard to management of atrial fibrillation, classes I and III are used in rhythm control as medical cardioversion agents, while classes II and IV are used as rate-control agents. Class III Class III agents predominantly, thereby prolonging repolarization. Since these agents do not affect the sodium channel, conduction velocity is not decreased. The prolongation of the action potential duration and refractory period, combined with the maintenance of normal conduction velocity, prevent re-entrant arrhythmias. (The re-entrant rhythm is less likely to interact with tissue that has become refractory). The class III agents exhibit reverse-use dependence (their potency increases with slower heart rates, and therefore improves maintenance of sinus rhythm).
Schedule 3 Controlled Substance List
Inhibiting potassium channels, slowing repolarization, results in slowed atrial-ventricular myocyte repolarization. Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development of polymorphic VT). Class III agents include:,,,,,.